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Drama and Discovery The Story of Histoplasmosis
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Thomas M. Daniel, Gerald L. Baum
Book Code: GM2162
ISBN: 0-313-32162-0
ISBN-13: 978-0-313-32162-7
192 pages, Figure, Maps, Photographs
Greenwood Press
Publication: 3/30/2002
List Price: $102.95 (UK Sterling Price: £59.95)
Availability: Out of stock
Media Type: Hardcover
Trim Size: 6 1/8 x 9 1/4
Subjects:
Series Title: Contributions in Medical Studies
Series Number: 48
Reviews:
  • Highly recommended for physicians, pathologists, medical historians, and graduate students.
    —Choice     October 2002
  • Although this is the story of histoplasmosis, it is apparent that it could be the story of a number of diseases in the manner that the reader is introduced to the unfolding of its mystery. The reader learns not only about the disease, but also about the teams of investigators and researchers working toward a common goal. Aside from being informative, this book also stimulates though on the evidence based medicine process. This book is highly recommended for academic libraries, especially those with departments in epidemiology and history of medicine programs.
    —E-Streams     March 2003
  • Endorsement From Lee B. Riechman, M.D., M.P.H.
    Professor of Medicine,Preventive Medicine and Communitiy Health
    Executive Director
    New Jersey Medical School
    National Tuberculosis Center:     Drama and Discovery:the Story of Histoplasmosis is a fascinating account of the detective work and dedication that led to a current knowledge about this twentieth century disease.
  • Endorsement From George W. Comstock, MD, DrPH, FACE
    Professor of Epidemiology
    The Johns Hopkins University:     Tom Daniel and Jerry Baum have done a masterful job of tracing the many-forked and often interrupted trail of events that have led to our present understanding of histoplasmosis, a fascinating and widespread disease of man, beast, and birds. A major bonus is that it reads like a novel!
  • Endorsement From John H. Bates, MD, S
    Deputy State Health Officer
    Professor of Medicine and Microbiology
    University of Arkansas College of Medicine:     The history of histoplasmosis as told by Baum and Daniel will be enjoyed by infectious disease experts and nonprofessionals having a keen interest in medical history and scientific discovery. Baum and Daniel write in an interesting and entertaining way, providing an element of mystery and medical detective work as their story unfolds.
Description: Histoplasmosis is a fungal disease that is widely endemic in much of the world. In the central United States, including the broad reaches of the Ohio and Mississippi River valleys, the majority of adults are infected with the causative fungus. Most infected individuals handle this infection well, but a few do become sick. Over the years there have been a number of outbreaks or epidemics with many persons becoming severely ill and some dying as a result. This is the story of the discovery of histoplasmosis in 1905 and the subsequent development of knowledge concerning its etiology, pathogenesis, epidemiology, diagnostic challenges, clinical manifestations, and treatment. Uniquely qualified to tell this tale, Daniel and Baum base their study on original source material not previously available. The story of histoplasmosis spans the twentieth century, from its discovery by Samuel Taylor Darling in Panama to the development of effective drug treatment near the century's end. The book epitomizes the growth of medical knowledge through the confluence of ideas and information arising from the work of many individual investigators, a recurrent theme in the history of medicine. Daniel and Baum include much original and previously unreported material derived from Baum's direct involvement with the unraveling of the pathogenesis of the disease and his personal knowledge of the people and events detailed in this book.
Table of Contents:
  • Introduction
  • All but One
  • In the Beginning
  • A Carpenter from Martinique, Samuel Taylor Darling, and Double Dose Discovery
  • The Bug, the Body, and the Battle
  • Rare to Well Done: Rocks in the Lungs and Two Tell-Tale Tests
  • Epidemics are for the Birds--and Bats
  • More than a Janus Disease
  • To Treat or Not to Treat
  • Glossary
  • Selected Bibliography
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